BDBM91594 Tropisetron

SMILES [H]C12CC[C@@H](C[C@H](C1)OC(=O)c1c[nH]c3ccccc13)N2C

InChI Key InChIKey=ZNRGQMMCGHDTEI-IAMFDIQRSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 91594   

TargetSoluble acetylcholine receptor(Aplysia Californica)
Uc San Diego

LigandPNGBDBM91594(Tropisetron)
Affinity DataKi:  109nM ΔG°:  -9.33kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Uc San Diego

LigandPNGBDBM91594(Tropisetron)
Affinity DataEC50:  92nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails