BDBM10036 1-[(2E)-2-(6,7-dihydro-1-benzothien-4(5H)-ylidene)ethyl]-1H-imidazole::1-{2-[(4E)-4,5,6,7-tetrahydro-1-benzothiophen-4-ylidene]ethyl}-1H-imidazole::CHEMBL57513::Tetrahydrobenzo[b]thiophene 35E

SMILES C(\C=C1/CCCc2sccc12)n1ccnc1

InChI Key InChIKey=RUTWVMBTFHJSGO-NYYWCZLTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10036   

TargetAromatase(Homo sapiens (Human))
Universitat Des Saarlandes

LigandPNGBDBM10036(1-[(2E)-2-(6,7-dihydro-1-benzothien-4(5H)-ylidene)...)
Affinity DataIC50:  680nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Universitat Des Saarlandes

LigandPNGBDBM10036(1-[(2E)-2-(6,7-dihydro-1-benzothien-4(5H)-ylidene)...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Universitat Des Saarlandes

LigandPNGBDBM10036(1-[(2E)-2-(6,7-dihydro-1-benzothien-4(5H)-ylidene)...)
Affinity DataIC50:  1.70E+3nMAssay Description:Thromboxane A2 synthase activity was assayed by measuring the fragmentation of prostaglandin H2 to form 12-hydroxy-5, 8,10-heptadecatrienoic acid and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed