BDBM102696 US8541572, 1003

SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(cc3)-c3nc(ccc3O)N3CCC(=O)CC3)C(=O)c2c1F

InChI Key InChIKey=SSCTWNVPCAPXGN-WJOKGBTCSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102696   

TargetTumor necrosis factor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102696(US8541572, 1003)
Affinity DataKi:  0.0826nM IC50:  124nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent