BDBM102872 US8541572, 2266

SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3cccnc3-c3cn[nH]c3)C(=O)c2c1

InChI Key InChIKey=YAUHDOATTPVDFL-HSZRJFAPSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102872   

TargetTumor necrosis factor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102872(US8541572, 2266)
Affinity DataKi:  0.120nM IC50:  927nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent