BDBM104009 DDR1-IN-1
SMILES CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(Oc3ccc4NC(=O)Cc4c3)c2)CC1
InChI Key InChIKey=AOZPVMOOEJAZGK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 104009
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital And Harvard Medical School
Massachusetts General Hospital And Harvard Medical School
Affinity DataEC50: 86nMAssay Description:The enzyme kinase assay was carried out using the Lanthascreen technology.More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital And Harvard Medical School
Massachusetts General Hospital And Harvard Medical School
Affinity DataIC50: 105nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital And Harvard Medical School
Massachusetts General Hospital And Harvard Medical School
Affinity DataIC50: 105nMAssay Description:Inhibition of human DDR1 kinase domain (601 to 913 residues) expressed in Sf9 cells by enzymatic kinase assayMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital And Harvard Medical School
Massachusetts General Hospital And Harvard Medical School
Affinity DataIC50: 86nMAssay Description:Inhibition of human DDR1 in doxycycline-stimulated human U2OS cells assessed as inhibition of collagen-1-induced autophosphorylation incubated for 1 ...More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Massachusetts General Hospital And Harvard Medical School
Massachusetts General Hospital And Harvard Medical School
Affinity DataIC50: 413nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair