BDBM106566 US8586600, II-52
SMILES Cc1cc(nc(Nc2cc(NC(=O)c3ccc(NC(=O)C=C)cc3)ccc2C)n1)-c1cccnc1
InChI Key InChIKey=TWVTXRXQEBZPJT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 106566
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 3.00E+3nMAssay Description:Compounds may be screened for their ability to inhibit KDR using a standard coupled enzyme assay (Fox et al., Protein Sci., (1998) 7, 2249).More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 1.02E+3nMAssay Description:Compounds may also be assayed as inhibitors of PDGFR in a manner substantially similar to the method described in Roberts, et al., Antiangiogen...More data for this Ligand-Target Pair