BDBM106566 US8586600, II-52

SMILES Cc1cc(nc(Nc2cc(NC(=O)c3ccc(NC(=O)C=C)cc3)ccc2C)n1)-c1cccnc1

InChI Key InChIKey=TWVTXRXQEBZPJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 106566   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Celgene Avilomics Research

US Patent
LigandPNGBDBM106566(US8586600, II-52)
Affinity DataIC50:  3.00E+3nMAssay Description:Compounds may be screened for their ability to inhibit KDR using a standard coupled enzyme assay (Fox et al., Protein Sci., (1998) 7, 2249).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Celgene Avilomics Research

US Patent
LigandPNGBDBM106566(US8586600, II-52)
Affinity DataIC50:  1.02E+3nMAssay Description:Compounds may also be assayed as inhibitors of PDGFR in a manner substantially similar to the method described in Roberts, et al., “Antiangiogen...More data for this Ligand-Target Pair
In DepthDetails US Patent