BDBM107105 US8592371, 8::US9278976, (3S,5R)-5-[2-(cyclopropanesulfonyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl]-2-(2,4,5-trifluorophenyl)oxan-3-amine

SMILES N[C@H]1C[C@H](COC1c1cc(F)c(F)cc1F)N1Cc2cn(nc2C1)S(=O)(=O)C1CC1

InChI Key InChIKey=AWJGMPKHYSURMN-HCUPATASSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107105   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM107105(US8592371, 8 | US9278976, (3S,5R)-5-[2-(cyclopropa...)
Affinity DataIC50:  1.90nMpH: 7.5 T: 2°CAssay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM107105(US8592371, 8 | US9278976, (3S,5R)-5-[2-(cyclopropa...)
Affinity DataIC50:  1.90nMAssay Description:Enzyme assay using dipeptidyl peptidase-IV.More data for this Ligand-Target Pair
In DepthDetails US Patent