BDBM108419 US8604206, 10::US8604206, 9

SMILES CC(O)[C@H]1CNC[C@@H](O)[C@@H]1O

InChI Key InChIKey=YEZMDJVWNQIFDP-UVSCYPECSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 108419   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108419(US8604206, 10 | US8604206, 9)
Affinity DataKi:  10nM IC50:  20nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108419(US8604206, 10 | US8604206, 9)
Affinity DataKi:  35nM IC50:  66nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108419(US8604206, 10 | US8604206, 9)
Affinity DataKi:  44nM IC50:  107nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Amicus Therapeutics

US Patent
LigandPNGBDBM108419(US8604206, 10 | US8604206, 9)
Affinity DataKi:  142nM IC50:  343nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In DepthDetails US Patent