BDBM109106 US8609852, 13

SMILES Cc1nc(cs1)C#Cc1cnc(nc1)-c1ccccc1C

InChI Key InChIKey=MTPUODLDZJCGLP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 109106   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM109106(US8609852, 13)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine from mGlu5R in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM109106(US8609852, 13)
Affinity DataKi:  0.600nM ΔG°:  -12.6kcal/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In DepthDetails US Patent