BDBM11236 (2S)-N-[(1S)-1-[(2-chloro-4-nitrophenyl)carbamoyl]-2-phenylethyl]-4-methyl-2-[(2S)-3-methyl-2-(thiophen-2-ylformamido)butanamido]pentanamide::Anilide Inhibitor 3h::N-(thien-2-ylcarbonyl)-L-valyl-L-leucyl-N-(2-chloro-4-nitrophenyl)-L-phenylalaninamide

SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)c1cccs1)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O

InChI Key InChIKey=BOBHTKXBEGQHHJ-KLJDGLGGSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11236   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11236((2S)-N-[(1S)-1-[(2-chloro-4-nitrophenyl)carbamoyl]...)
Affinity DataKi:  2.29E+3nM ΔG°:  -7.69kcal/mole IC50:  5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
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