BDBM112438 US8623889, 437

SMILES C[C@@H]1CCC(=O)N1c1ccc2cc(NC(=O)C3C[C@@H]3F)ncc2c1

InChI Key InChIKey=WRGQMIQWFKFVTM-PYUGYUQBSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 112438   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112438(US8623889, 437)
Affinity DataKi:  0.0799nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112438(US8623889, 437)
Affinity DataKi:  3.40nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent