BDBM11246 AG7088 analogue 1d::ethyl (2E,4S)-4-[(2R,5S)-2-benzyl-5-{[(benzyloxy)carbonyl]amino}-6-methyl-4-oxoheptanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate::med.21724, Compound 36

SMILES CCOC(=O)\C=C\[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@@H](CC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)Cc1ccccc1

InChI Key InChIKey=NNUSBUJYBPVXNX-MPJJSOSNSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11246   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11246(AG7088 analogue 1d | ethyl (2E,4S)-4-[(2R,5S)-2-be...)
Affinity DataKi:  2.26E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
University Of Bonn

LigandPNGBDBM11246(AG7088 analogue 1d | ethyl (2E,4S)-4-[(2R,5S)-2-be...)
Affinity DataIC50:  1.32E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11246(AG7088 analogue 1d | ethyl (2E,4S)-4-[(2R,5S)-2-be...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed