BDBM11262 dipeptidomimetic unsaturated ester 18d::ethyl (2E,4S)-4-({N-[(2E)-3-(2,4-dimethoxyphenyl)prop-2-enoyl]-L-phenylalanyl}amino)-5-phenylpent-2-enoate::ethyl (2E,4S)-4-[(2S)-2-[(2E)-3-(2,4-dimethoxyphenyl)prop-2-enamido]-3-phenylpropanamido]-5-phenylpent-2-enoate::jm5b01461, Compound 9

SMILES CCOC(=O)\C=C\[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccc(OC)cc1OC

InChI Key InChIKey=ACACSUQRMWRCPB-FUNSLCGPSA-N

Data  2 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11262   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11262(dipeptidomimetic unsaturated ester 18d | ethyl (2E...)
Affinity DataKi:  9.04E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11262(dipeptidomimetic unsaturated ester 18d | ethyl (2E...)
Affinity DataKi:  9.05E+3nM ΔG°:  -6.88kcal/mole IC50:  1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11262(dipeptidomimetic unsaturated ester 18d | ethyl (2E...)
Affinity DataEC50:  110nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM11262(dipeptidomimetic unsaturated ester 18d | ethyl (2E...)
Affinity DataIC50:  1.00E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed