BDBM11265 N-(4-chlorophenyl)-2-[(4-{5-[1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl}pyrimidin-2-yl)sulfanyl]acetamide::acs.jmedchem.1c00409_ST.511::jm5b01461, Compound 106::pyrimidine-containing compound 2

SMILES Cn1nc(cc1C(F)(F)F)-c1ccc(s1)-c1ccnc(SCC(=O)Nc2ccc(Cl)cc2)n1

InChI Key InChIKey=AWQBIBTZJKFLEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11265   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11265(N-(4-chlorophenyl)-2-[(4-{5-[1-methyl-5-(trifluoro...)
Affinity DataIC50:  1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11265(N-(4-chlorophenyl)-2-[(4-{5-[1-methyl-5-(trifluoro...)
Affinity DataIC50:  1.00E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Tsing Hua University

LigandPNGBDBM11265(N-(4-chlorophenyl)-2-[(4-{5-[1-methyl-5-(trifluoro...)
Affinity DataIC50:  1.00E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed