BDBM11267 N-(2-chlorophenyl)-2-({4-[4-methyl-5-(4-methyl-1,3-thiazol-2-yl)-2-(methylsulfanyl)thiophen-3-yl]pyrimidin-2-yl}sulfanyl)acetamide::acs.jmedchem.1c00409_ST.536::pyrimidine-containing compound 4

SMILES CSc1sc(c(C)c1-c1ccnc(SCC(=O)Nc2ccccc2Cl)n1)-c1nc(C)cs1

InChI Key InChIKey=NNVVKOVHRSDRSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11267   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University

LigandPNGBDBM11267(N-(2-chlorophenyl)-2-({4-[4-methyl-5-(4-methyl-1,3...)
Affinity DataIC50:  1.20E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University

LigandPNGBDBM11267(N-(2-chlorophenyl)-2-({4-[4-methyl-5-(4-methyl-1,3...)
Affinity DataIC50:  1.20E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed