BDBM11463 CHEMBL22310::N-{4-[(1S)-1-amino-2-[(3S)-3-fluoropyrrolidin-1-yl]-2-oxoethyl]cyclohexyl}-2,4-difluorobenzene-1-sulfonamide::difluorobenzenesulfonamide 1
SMILES [H][C@@]1(CC[C@@H](CC1)NS(=O)(=O)c1ccc(F)cc1F)[C@H](N)C(=O)N1CC[C@H](F)C1
InChI Key InChIKey=QTZTUCOZZMQUFY-MJFSBKNWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 11463
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.90E+4nMAssay Description:Binding affinity of the compound towards human ERG potassium ion channel was determinedMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.90E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 2.72E+3nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against human Dipeptidyl-peptidase IVMore data for this Ligand-Target Pair
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against human quiescent cell proline dipeptidase (QPP) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 993nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair