BDBM11589 1c-para-F::5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-(4-fluorophenyl)pyrimidin-4-amine::Aminomethylpyrimidine 1ck

SMILES NCc1c(N)nc(nc1-c1ccc(Cl)cc1Cl)-c1ccc(F)cc1

InChI Key InChIKey=OVTWFYBUKKHDFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11589   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Hoffmann-La Roche

LigandPNGBDBM11589(1c-para-F | 5-(aminomethyl)-6-(2,4-dichlorophenyl)...)
Affinity DataIC50:  0.200nMAssay Description:DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed