BDBM11822 (3R,4R)-3-(isonicotinoylamino)azepan-4-yl 4-(2-fluoro-6-hydroxy-3-methoxybenzoyl)benzoate dihydrochloride::(3R,4R)-3-(pyridine-4-amido)azepan-4-yl 4-[(2-fluoro-6-hydroxy-3-methoxyphenyl)carbonyl]benzoate dihydrochloride::Azepane Derivative 1

SMILES COc1ccc(O)c(C(=O)c2ccc(cc2)C(=O)O[C@@H]2CCCNC[C@H]2NC(=O)c2ccncc2)c1F

InChI Key InChIKey=VYPRIFLEMOQRJK-TZIWHRDSSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11822   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Roche Diagnostics

LigandPNGBDBM11822((3R,4R)-3-(isonicotinoylamino)azepan-4-yl 4-(2-flu...)
Affinity DataIC50:  5nMpH: 7.2 T: 2°CAssay Description:In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Roche Diagnostics

LigandPNGBDBM11822((3R,4R)-3-(isonicotinoylamino)azepan-4-yl 4-(2-flu...)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:An ELISA-based assay has been developed for the serine/threonine kinase, PKB-alpha. The assay utilizes an N-terminally biotinylated substrate peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed