BDBM11940 2-AMP::2-Adenylic acid::Adenosine 2-monophosphate::{[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1OP(O)(O)=O

InChI Key InChIKey=QDFHPFSBQFLLSW-KQYNXXCUSA-N

Data  1 IC50  1 EC50  1 ITC

PDB links: 20 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11940   

TargetAdenosine receptor A1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL

LigandBDBM11940(2-AMP | 2-Adenylic acid | Adenosine 2-monophosphat...)Copy SMILESCopy InChI

Affinity DataEC50:  490nMAssay Description:Agonist activity at human A1AR expressed in HEK293T/17 cells assessed as inhibition of isoproterenol-induced cAMP accumulation incubated for 10 mins ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
KEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetInositol monophosphatase 1(Bos taurus)
TBA

Curated by ChEMBL

LigandBDBM11940(2-AMP | 2-Adenylic acid | Adenosine 2-monophosphat...)Copy SMILESCopy InChI

Affinity DataIC50:  1.30E+6nMAssay Description:Tested for the inhibitory activity against bovine inositol monophosphatase by measuring concentration inhibiting the production of [14C]-inositol fro...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseChEBI
KEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails Article
Copy BDB DOI