BDBM119440 BDBM119696::US8685986, 15

SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccoc2)-c2ccc(O)cc2)cc1

InChI Key InChIKey=OUFJXJJAONPLLU-UHFFFAOYSA-N

Data  1 KI  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 119440   

TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataKi:  9.40nM ΔG°:  -11.1kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  144nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  46.1nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  338nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  72nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  178nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  74.8nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  59nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  35nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  49.9nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119440(BDBM119696 | US8685986, 15)
Affinity DataIC50:  60nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent