BDBM119876 SL932::US9073941, 503

SMILES COc1ccc(NC(=O)CN(C)S(=O)(=O)c2cc(Br)cnc2N)cc1Cl

InChI Key InChIKey=VKUCSZWNAXJXMH-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 119876   

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119876(SL932 | US9073941, 503)
Affinity DataKi:  37nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119876(SL932 | US9073941, 503)
Affinity DataKi:  78nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Academia Sinica

US Patent
LigandPNGBDBM119876(SL932 | US9073941, 503)
Affinity DataIC50:  700nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair
In DepthDetails US Patent