BDBM124179 US8754075, 50

SMILES CC#CCOc1cnc(cn1)C(=O)Nc1ccc(F)c(c1)[C@@]1(C)N=C(N)OC[C@]1(C)F

InChI Key InChIKey=MVLCYGXVHAGUKG-LEWJYISDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124179   

TargetBeta-secretase 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM124179(US8754075, 50)
Affinity DataIC50:  0.100nMT: 2°CAssay Description:The assay uses the principle of inhibition of human TMEM27 cleavage by endogenous cellular BACE2 in the Ins1e rat cell line and shedding from the cel...More data for this Ligand-Target Pair
In DepthDetails US Patent