BDBM13275 BMS-354825 2-Heteroarylamino-thiazole Analog 12t::N-(2-Chloro-6-methylphenyl)-2-(2-methyl-6-morpholinopyrimidin-4-ylamino)-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-{[2-methyl-6-(morpholin-4-yl)pyrimidin-4-yl]amino}-1,3-thiazole-5-carboxamide

SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cc(nc(C)n2)N2CCOCC2)s1

InChI Key InChIKey=JXKNOTHMBHBSTI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13275   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM13275(BMS-354825 2-Heteroarylamino-thiazole Analog 12t |...)
Affinity DataIC50:  1.30nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed