BDBM13755 (1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)adamantane-1-carboxylic acid::adamantane ether 5
SMILES CC(C)(Oc1ccccc1)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(O)=O
InChI Key InChIKey=GIFJUNAMCWBYRP-ZXNQMZRGSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 13755
Affinity DataIC50: 39nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp...More data for this Ligand-Target Pair
Affinity DataIC50: 38.9nMAssay Description:Inhibition of 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp...More data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair