BDBM13952 2-(Naphthalen-1-yloxalylamino)benzoic Acid::2-(naphthalen-1-ylamidoformic acid)benzoic acid::CHEMBL64934::naphthyloxamic acid 5

SMILES OC(=O)C(=O)N(c1ccccc1C(O)=O)c1cccc2ccccc12

InChI Key InChIKey=WQWCUHJIERBOSM-UHFFFAOYSA-N

Data  5 KI  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 13952   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  2.40E+4nM ΔG°:  -6.23kcal/mole Kd:  2.60E+4nMpH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  3.90E+4nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  3.90E+4nM ΔG°:  -5.95kcal/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  4.40E+4nM ΔG°:  -5.88kcal/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  1.58E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKd:  2.60E+4nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair