BDBM142451 US8933224, 44

SMILES Cc1nc([C@@H]2CCOC2)c2c(ncnn12)N1CCc2nn(C)c(C3CC3)c2C1

InChI Key InChIKey=SYRPJHKMGQGRQF-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142451   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM142451(US8933224, 44)
Affinity DataIC50:  0.110nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Pfizer

US Patent
LigandPNGBDBM142451(US8933224, 44)
Affinity DataIC50:  0.102nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In DepthDetails US Patent