BDBM14751 (R)-4-[3-(3-Ethoxy-phenoxy)-pyrrolidin-1-yl]-6,7-dimethoxy-quinazoline::4-[(3R)-3-(3-ethoxyphenoxy)pyrrolidin-1-yl]-6,7-dimethoxyquinazoline::6,7-Dimethoxy-4-pyrrolidylquinazoline 14
SMILES CCOc1cccc(O[C@@H]2CCN(C2)c2ncnc3cc(OC)c(OC)cc23)c1
InChI Key InChIKey=WUQPRMFKNDQDDT-QGZVFWFLSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 14751
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
St. John'S University
Curated by ChEMBL
St. John'S University
Curated by ChEMBL
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
St. John'S University
Curated by ChEMBL
St. John'S University
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
St. John'S University
Curated by ChEMBL
St. John'S University
Curated by ChEMBL
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
St. John'S University
Curated by ChEMBL
St. John'S University
Curated by ChEMBL
Affinity DataKi: 88nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Pfizer
Pfizer
Affinity DataKi: 94nM ΔG°: -9.48kcal/molepH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
St. John'S University
Curated by ChEMBL
St. John'S University
Curated by ChEMBL