BDBM14864 5-azaindole analog 2::{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}phenyl)phenyl]methyl}urea

SMILES NC(=O)NCc1cccc(c1)-c1cccc(-c2cc3cnccc3[nH]2)c1O

InChI Key InChIKey=SRPOHNDQBDHONJ-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 14864   

TargetCoagulation factor VII(Homo sapiens (Human))
Celera

LigandPNGBDBM14864(5-azaindole analog 2 | {[3-(2-hydroxy-3-{1H-pyrrol...)
Affinity DataKi:  800nM ΔG°:  -8.23kcal/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14864(5-azaindole analog 2 | {[3-(2-hydroxy-3-{1H-pyrrol...)
Affinity DataKi:  4.65E+4nM ΔG°:  -5.85kcal/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14864(5-azaindole analog 2 | {[3-(2-hydroxy-3-{1H-pyrrol...)
Affinity DataKi:  7.15E+4nM ΔG°:  -5.59kcal/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14864(5-azaindole analog 2 | {[3-(2-hydroxy-3-{1H-pyrrol...)
Affinity DataKi:  1.25E+5nM ΔG°:  -5.27kcal/molepH: 7.4 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed