BDBM158157 US10081622, Compound 18::US9029356, 18::US9255087, 18::US9616059, 18
SMILES CN1CCN(CC1)c1ccc(C(=O)Nc2n[nH]c3ccc(Cc4cc(F)cc(F)c4)cc23)c(NC2CCCCC2)c1
InChI Key InChIKey=VHSQRCDULUNORA-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 158157
Affinity DataIC50: 1.77E+3nMpH: 7.5Assay Description:ALK enzyme needs pre-activation in order to linearize reaction kinetics.Kinase Buffer (KB) for ALKKinase buffer was composed of 50 mM HEPES pH 7.5 co...More data for this Ligand-Target Pair
Affinity DataIC50: 6.07E+3nMAssay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.A spe...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant ALK (unknown origin) in presence of gamma33-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of IR (unknown origin) in presence of gamma33-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.23E+3nMAssay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.A spe...More data for this Ligand-Target Pair