BDBM161399 US10124003, Ex. Compound 12::US10835536, Ex. Comp 12::US10894048, Ex Comp 12::US9108973, 12

SMILES COc1cc(OC)cc(c1)C#Cc1nn(C2CN(C2)C(=O)\C=C\CN(C)C)c2ncnc(N)c12

InChI Key InChIKey=HBIDSBZKIOZROC-AATRIKPKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 161399   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161399(US10124003, Ex. Compound 12 | US10835536, Ex. Comp...)
Affinity DataIC50:  2.20nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161399(US10124003, Ex. Compound 12 | US10835536, Ex. Comp...)
Affinity DataIC50:  2.20nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161399(US10124003, Ex. Compound 12 | US10835536, Ex. Comp...)
Affinity DataIC50:  2.20nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161399(US10124003, Ex. Compound 12 | US10835536, Ex. Comp...)
Affinity DataIC50:  2.20nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails US Patent