BDBM16313 2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamothioyl}-5-fluorophenoxy)acetic acid::CHEMBL395347::IDD 594::IDD594::LdT::{2-[(4-bromo-2-fluorobenzyl)carbamothioyl]-5-fluorophenoxy}acetic acid
SMILES OC(=O)COc1cc(F)ccc1C(=S)NCc1ccc(Br)cc1F
InChI Key InChIKey=JCZUIWYXULSXSW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 16313
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Affinity DataIC50: 3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Affinity DataIC50: 30nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire
Affinity DataIC50: 30nMAssay Description:Inhibition of AR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of ALR1 (unknown origin)More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 16313
ITC DataΔG°: -9.77kcal/mole logk: 1.49E+7
T: 24.85°C
T: 24.85°C