BDBM16431 2-(naphthalen-2-yl)acetic acid::2-Napthylacetic acid::Betoxan::CHEMBL948::beta-Naphthylacetic acid::naphthalen-2-ylacetic acid

SMILES OC(=O)Cc1ccc2ccccc2c1

InChI Key InChIKey=VIBOGIYPPWLDTI-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16431   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16431(2-(naphthalen-2-yl)acetic acid | 2-Napthylacetic a...)
Affinity DataKi:  6.20E+3nM ΔG°:  -7.10kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [W220Y,C299A](Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16431(2-(naphthalen-2-yl)acetic acid | 2-Napthylacetic a...)
Affinity DataKi:  9.40E+4nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Brown University

Curated by ChEMBL
LigandPNGBDBM16431(2-(naphthalen-2-yl)acetic acid | 2-Napthylacetic a...)
Affinity DataIC50:  3.50E+6nMAssay Description:Inhibitory activity against Yersinia Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed