BDBM16478 2-[5-(benzyloxy)-3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]-1H-indol-1-yl]acetic acid::Indoleacetic Acid Inhibitor 36

SMILES OC(=O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cc(OCc3ccccc3)ccc12

InChI Key InChIKey=VVWULALTONIGFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16478   

TargetAldo-keto reductase family 1 member A1(Homo sapiens (Human))
The Institute For Diabetes Discovery

LigandPNGBDBM16478(2-[5-(benzyloxy)-3-[(4,5,7-trifluoro-1,3-benzothia...)
Affinity DataIC50:  4.80E+3nMAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappear...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
The Institute For Diabetes Discovery

LigandPNGBDBM16478(2-[5-(benzyloxy)-3-[(4,5,7-trifluoro-1,3-benzothia...)
Affinity DataIC50:  12nMAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappear...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed