BDBM16634 6-{[3-methyl-5-(trifluoromethyl)-1-benzofuran-2-]sulfonyl}-2,3-dihydropyridazin-3-one::Heterocyclic Sulfonylpyridazinone, 19p

SMILES Cc1c(oc2ccc(cc12)C(F)(F)F)S(=O)(=O)c1ccc(=O)[nH]n1

InChI Key InChIKey=DXMRTFOZJATGPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16634   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM16634(6-{[3-methyl-5-(trifluoromethyl)-1-benzofuran-2-]s...)
Affinity DataIC50:  5nMAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed