BDBM166646 4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobutanoic acid (5)
SMILES OC(=O)CCC(=O)Nc1ccc(NC(=O)c2ccco2)cc1
InChI Key InChIKey=QTKDRUABFJMKRT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 166646
Affinity DataIC50: 1.29E+4nMpH: 7.5Assay Description:Initially, equimolar quantities of about 0.5µM each of E. coli gyraseA and S. aureus gyraseB were incubated for a period of 45 min with salmon sperm ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B ATPase activityMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Birla Institute Of Technology & Science-Pilani
Curated by ChEMBL
Birla Institute Of Technology & Science-Pilani
Curated by ChEMBL
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase-mediated supercoiling of relaxed DNA using pBR 322 as substrate by agarose gel electrophoresis analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.12E+3nMpH: 7.6 T: 2°CAssay Description:Supercoiling assay was performed using the commercially available kit (DNA gyrase supercoiling assay kit: SAS4001) from Inspiralis Pvt.limited, Norwi...More data for this Ligand-Target Pair