BDBM166667 N-(4-(4-Hydrazinyl-4-oxobutanamido)phenyl)-5-nitrothiophene-2-carboxamide (26)

SMILES NNC(=O)CCC(=O)Nc1ccc(NC(=O)c2ccc(s2)[N+]([O-])=O)cc1

InChI Key InChIKey=JVWAGGIDYKWXGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 166667   

TargetDNA gyrase subunit B(Staphylococcus aureus)
Birla Institute Of Technology

LigandPNGBDBM166667(N-(4-(4-Hydrazinyl-4-oxobutanamido)phenyl)-5-nitro...)
Affinity DataIC50:  1.93E+4nMpH: 7.6 T: 2°CAssay Description:Supercoiling assay was performed using the commercially available kit (DNA gyrase supercoiling assay kit: SAS4001) from Inspiralis Pvt.limited, Norwi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Birla Institute Of Technology

LigandPNGBDBM166667(N-(4-(4-Hydrazinyl-4-oxobutanamido)phenyl)-5-nitro...)
Affinity DataIC50:  2.64E+4nMpH: 7.5Assay Description:Initially, equimolar quantities of about 0.5µM each of E. coli gyraseA and S. aureus gyraseB were incubated for a period of 45 min with salmon sperm ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed