BDBM167191 US9073876, 272::US9732093, Compound 272

SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2nc(N)c3ccccc3n2)c1F

InChI Key InChIKey=WCCMLGFOOPCMNI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 167191   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM167191(US9073876, 272 | US9732093, Compound 272)
Affinity DataKi:  0.5nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFlap endonuclease 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM167191(US9073876, 272 | US9732093, Compound 272)
Affinity DataKi:  0.5nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFlap endonuclease 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM167191(US9073876, 272 | US9732093, Compound 272)
Affinity DataKi:  0.5nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails US Patent