BDBM17048 Indolinone based inhibitor, 4j::[(3Z)-2-oxo-3-[1-(1H-pyrrol-2-yl)propylidene]-2,3-dihydro-1H-indol-5-yl]urea

SMILES CC\C(=C1\C(=O)Nc2ccc(NC(N)=O)cc12)c1ccc[nH]1

InChI Key InChIKey=ONFAWAGNIRCQMX-UVTDQMKNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17048   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17048(Indolinone based inhibitor, 4j | [(3Z)-2-oxo-3-[1-...)
Affinity DataIC50:  3nMAssay Description:The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed