BDBM173348 US10323032, Example 66::US9096596, 66::US9604982, Example 66
SMILES C[C@@H]1Cc2c(CN1C(=O)c1ccc(F)c(c1Cl)C(F)(F)F)nc(C)nc2-c1ccn[nH]1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 173348
Affinity DataKi: 50nMAssay Description:Displacement of [3H]A-804598 from human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 50.1nMAssay Description:Human or rat P2X7-1321 N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
Affinity DataKi: 50.1nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
Affinity DataKi: 50.1nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
Affinity DataKi: 50.1nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity against rat recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ flux...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity against human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ fl...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high gluc...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high gluc...More data for this Ligand-Target Pair