BDBM17748 2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline::4-(6,7-dimethylquinoxalin-2-yl)benzene-1,2-diol::AG1433::SU 1433

SMILES Cc1cc2ncc(nc2cc1C)-c1ccc(O)c(O)c1

InChI Key InChIKey=SMKFYHOKXJUJOT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17748   

TargetMacrophage colony-stimulating factor 1 receptor [538-972]()
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17748(2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline | ...)
Affinity DataIC50:  1.00E+4nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Human Sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17748(2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline | ...)
Affinity DataIC50:  9.40E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor [538-678,753-922](Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17748(2-(3,4-Dihydroxyphenyl)-6,7-dimethylquinoxaline | ...)
Affinity DataIC50:  8.30E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed