BDBM179297 US9126947, 18

SMILES C[C@@H](Oc1cc(nnc1N)C(=O)Nc1ccc(cc1)C(=O)N1C[C@H](C)N[C@H](C)C1)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=GLYMPHUVMRFTFV-QLFBSQMISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 179297   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Xcovery Holding

US Patent
LigandPNGBDBM179297(US9126947, 18)
Affinity DataIC50: <1nMT: 2°CAssay Description:Assays were performed as described in Fabian et al. (2005) Nature Biotechnology, vol. 23, p. 329 and in Karaman et al. (2008) Nature Biotechnology, v...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM179297(US9126947, 18)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of c-MET (unknown origin) by kinome scan-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Xcovery Holding

US Patent
LigandPNGBDBM179297(US9126947, 18)
Affinity DataIC50: <0.400nMAssay Description:Inhibition of ALK (unknown origin) by kinome scan-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed