BDBM18045 5-(PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE::5-(phenylsulfanyl)quinazoline-2,4-diamine::GW997

SMILES Nc1nc(N)c2c(Sc3ccccc3)cccc2n1

InChI Key InChIKey=BUFDQCGCADQQQY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18045   

TargetDihydrofolate reductase(Homo sapiens (Human))
Gsk

LigandPNGBDBM18045(5-(PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE | 5-(phe...)
Affinity DataIC50:  620nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Candida albicans)
Gsk

LigandPNGBDBM18045(5-(PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE | 5-(phe...)
Affinity DataIC50:  34nMpH: 6.4 T: 2°CAssay Description:IC50 is the concentration of inhibitor that decreases the velocity of the standard assay by 50%. The enzyme, NADPH, and varying concentrations of inh...More data for this Ligand-Target Pair