BDBM180952 US9133187, I-66

SMILES CNC[C@@H](NC(=O)N1CCc2cnc(NC(C)C)nc2C1)c1ccc(c(F)c1)C(F)(F)F

InChI Key InChIKey=KHUJYHUWBNIPAC-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180952   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM180952(US9133187, I-66)
Affinity DataIC50:  4.10nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent