BDBM181005 US9133187, II-366

SMILES CC1CC(CCO1)Nc1ncc2CCN(Cc2n1)C(=O)N[C@H](CO)c1ccc(Cl)c(F)c1

InChI Key InChIKey=GAEATSLEUUPQFD-VRGJXPMKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 181005   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM181005(US9133187, II-366)
Affinity DataIC50:  2.39nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent