BDBM18244 6-[(2-iodo-5-methoxyphenyl)methyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine::Piritrexim analogue, 56
SMILES COc1ccc(I)c(Cc2cnc3nc(N)nc(N)c3c2C)c1
InChI Key InChIKey=JLYBTCUUMJBPSE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 18244
Affinity DataIC50: 3.80nMpH: 7.4 T: 2°CAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Harvard Medical School
Affinity DataIC50: 5.80nMAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair