BDBM182848 US9149492, Eflucimibe (F12511)

SMILES CCCCCCCCCCCCS[C@H](C(=O)Nc1cc(C)c(O)c(C)c1C)c1ccccc1

InChI Key InChIKey=ZXEIEKDGPVTZLD-NDEPHWFRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 182848   

TargetSterol O-acyltransferase 2(Homo sapiens (Human))
Dartmouth College

US Patent
LigandPNGBDBM182848(US9149492, Eflucimibe (F12511))
Affinity DataIC50:  110nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dartmouth College

US Patent
LigandPNGBDBM182848(US9149492, Eflucimibe (F12511))
Affinity DataIC50:  39nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent