BDBM18378 Pyridyl substituted pyrrole compound, 13::sodium (3R,5R)-7-[5-(ethylcarbamoyl)-3-(4-fluorophenyl)-1-(propan-2-yl)-4-(pyridin-2-yl)-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate

SMILES CCNC(=O)c1c(c(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n1C(C)C)-c1ccc(F)cc1)-c1ccccn1

InChI Key InChIKey=RZGLXXTZOCSIRX-NHCUHLMSSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18378   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM18378(Pyridyl substituted pyrrole compound, 13 | sodium ...)
Affinity DataIC50:  21nMpH: 7.2 T: 2°CAssay Description:Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme source...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed