BDBM191574 6-(3-bromophenyl)pteridine-2,4,7-triamine (18)

SMILES Nc1nc(N)c2nc(c(N)nc2n1)-c1cccc(Br)c1

InChI Key InChIKey=UWFFWZGQGRBIBG-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191574   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

LigandPNGBDBM191574(6-(3-bromophenyl)pteridine-2,4,7-triamine (18))
Affinity DataIC50:  2.50E+3nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Max Planck Institute Of Molecular Physiology

LigandPNGBDBM191574(6-(3-bromophenyl)pteridine-2,4,7-triamine (18))
Affinity DataIC50:  9.30E+3nMAssay Description:Single-point measurements analyses and subsequent dose-dependent investigations of selected pteridine derivatives for inhibition of CK1α were pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed