BDBM19236 2-{2-bromo-5-[4-({[(2,4-difluorophenyl)methyl](3-methanesulfonamido-2-methylphenyl)amino}methyl)phenoxy]phenoxy}acetic acid::GR sulfonamide modulator, 13

SMILES Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(Oc2ccc(Br)c(OCC(O)=O)c2)cc1)Cc1ccc(F)cc1F

InChI Key InChIKey=CFZKPYJJGYQRFD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19236   

TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19236(2-{2-bromo-5-[4-({[(2,4-difluorophenyl)methyl](3-m...)
Affinity DataIC50:  140nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19236(2-{2-bromo-5-[4-({[(2,4-difluorophenyl)methyl](3-m...)
Affinity DataIC50:  1.80nM EC50:  330nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the 3(H)-dexamethasone from the receptor an IC50 value (the concentration required to inhibit 50% of the binding of 3(...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed