BDBM192766 4-MMPB

SMILES CN1CCN(CC1)c1nc(C)c2Nc3ccccc3Sc2n1

InChI Key InChIKey=HYPHGMNLWIKEMB-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 192766   

TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))TBA
LigandPNGBDBM192766(4-MMPB)
Affinity DataKi:  198nMAssay Description:Inhibition of Glycine max (soybean) 15-lipoxygenase activity assessed as decrease in peroxide formation using linoleic acid as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))TBA
LigandPNGBDBM192766(4-MMPB)
Affinity DataKi:  204nMAssay Description:Inhibition of Glycine max (soybean) 15-lipoxygenase activity assessed as decrease in peroxide formation using linoleic acid as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))TBA
LigandPNGBDBM192766(4-MMPB)
Affinity DataIC50:  4.17E+4nMAssay Description:Competitive inhibition of Glycine max (soybean) 15-lipoxygenase activity using linoleic acid as substrate by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLipoxygenase(Glycine max)
The Medical University Of Silesia

Curated by ChEMBL
LigandPNGBDBM192766(4-MMPB)
Affinity DataIC50:  2.12E+4nMAssay Description:Inhibition of soybean lipoxygenase using linoleic acid as substrate preincubated for 5 mins followed by substrate addition measuredf after 7 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))TBA
LigandPNGBDBM192766(4-MMPB)
Affinity DataIC50:  2.26E+4nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))TBA
LigandPNGBDBM192766(4-MMPB)
Affinity DataIC50:  4.17E+4nMAssay Description:Competitive inhibition of Glycine max (soybean) 15-lipoxygenase activity using linoleic acid as substrate by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article